Pharmacokinetics of chloramphenicol in sheep after intravenous, intramuscular and subcutaneous administration
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منابع مشابه
Pharmacokinetics of Cefepime Following Intravenous and Intramuscular Administration in Sheep
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متن کاملPharmacokinetics of diclofenac in sheep following intravenous and intramuscular administration.
OBJECTIVES The aim of this work was to examine the pharmacokinetics of diclofenac (DCLF) in sheep after intravenous (IV) and intramuscular (IM) dosing. ANIMALS Healthy male Najdi sheep. MATERIALS AND METHODS Diclofenac (1 mg kg(-1)) was administered to ten clinically healthy-male Najdi sheep IV or IM (n = 5 each). Blood samples (5 mL) were collected and serum was separated for drug analysis...
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Ceftiofur sodium administered as a single dose (2.2 mg/kg, IV and SC) resulted in plasma concentrations of active drug similar to those achieved with the approved IM route. By varying dosing intervals after appropriate concentrations are achieved by IV, SC or IM administration should be effective for treatment of bacterial infections caused by susceptible organisms. Therefore, dosage intervals ...
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The pharmacokinetic parameters of ceftazidime, a third generation cephalosporin, were investigated in six buffalo calves after single intravenous (IV) and intramuscular (IM) administration at a dose rate of 10 mg/kg body weight. Ceftazidime concentrations in plasma and urine were determined by microbiological assay. Ceftazidime disposition was best fitted by a two-compartmental and a one-compar...
متن کاملPharmacokinetics of ceftriaxone in buffalo calves (Bubalus bubalis) following intravenous and intramuscular administration
Pharmacokinetics of ceftriaxone was studied in buffalo calves (Bubalus bubalis) after single intravenousand intramuscular administration of 10 mg/kg body weight. The drug concentrations in plasma samples weremeasured by high performance liquid chromatography with UV detection. Following intravenousadministration, the drug was rapidly distributed (Cpo: 106.5 ± 9.64 μg/ml; t1/2α: 0.09 ± 0.01 h; V...
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ژورنال
عنوان ژورنال: Veterinary Quarterly
سال: 1990
ISSN: 0165-2176,1875-5941
DOI: 10.1080/01652176.1990.9694262